PET-CT Scanning: Revolutionising Cancer Detection and Treatment Monitoring

Positron emission tomography (PET) is one of the most promising medical imaging technologies currently available in the medical world. It uses a small amount of radioactive tracers or radiopharmaceuticals to visualise molecular processes in the body. By measuring changes at the cellular level, the modality may help evaluate the disease before other imaging tests. It is an accurate imaging method that helps in the diagnosis, staging, restaging, and therapeutic monitoring of many common cancers.

What is PET/CT scanning?

PET imaging or a PET scan is a type of nuclear medicine imaging. It combines computed tomography (CT) and PET in one single imaging method and presents results that help doctors in making treatment decisions. While the PET image reveals the functioning of the body, the CT image tells about the anatomic structure.

If you live in Delhi-NCR, you can do an online search to know PET CT scan price.

How does a PET-CT work?

For this test, a PET radiotracer 18F-fluorodeoxyglucose (FDG), derived from a simple sugar, is injected into the patient’s bloodstream. The FDG radiotracer gets accumulated in the body’s organs and tissues. The areas of higher FDG uptake are called ‘hot spots’ due to the occurrence of high levels of chemical activity. A PET scan is performed to create a 3D model of the metabolic activity in the body. Thereafter, a CT Scan is taken to create a highly detailed anatomical image of the area. Some of the specific areas of high FDG accumulation include salivary glands, brain, myocardium, gastrointestinal tract, gonadal tissues, urinary tract and thyroid gland. In addition, FDG can also show a higher uptake in areas of infection, tumour, and inflammation.

Why is it done?

This modality is used for various purposes, but the most common use of PET involves diagnosis, monitoring and guiding treatment for the following:

1. Cancer

Cancer cells show up as bright spots due to the fact that they consume more energy than regular cells. It is often combined with CT or MRI to get a highly detailed visualisation of organs and tissues. The scan is useful in finding out:

    • Cancer

    • Check the spread

    • Checking the effectiveness of treatment

    • Finding a recurrence

Common cancers that PET-CT/PET-MRI can detect include:

Brain, breast, skin, thyroid, oesophageal, cervical, pancreatic, prostate, colorectal, lymphatic system, head & neck, lung.

2. Heart Disease

This scan is often recommended to check the flow of blood in the heart. It can appear useful to decide if a patient needs angioplasty or a bypass surgery.

3. Brain Disorders

This scan helps healthcare providers to assess normal and abnormal changes in the brain. In neuroimaging, they can help help healthcare providers to asses infections, inflammation, and neurodegenerative diseases, by visualising amyloid or tau deposits, glucose and amino acid metabolism, and dopamine receptor activity.

It aids in evaluating and monitoring brain conditions such as:

    • Alzheimer’s disease

    • Seizure disorders

    • Brain tumours

PET CT scan cost will vary depending on the location of the facility and the type of lab.

Benefits of PET-CT

A PET-CT is commonly used in the field of oncology as it provides valuable information which would be otherwise non-attainable using other imaging modalities. The primary areas for which this modality is used includes:

Diagnosis: The scan is useful in finding out changes at the cellular level, which makes it easier to detect cancer in its early stages when treatment is more effective.

Staging: It offers healthcare providers information regarding the location and spread of diseases, especially cancers. It helps in staging the disease and planning appropriate treatment.

Treatment monitoring: PET CT scans give relevant information about the function and structure of tissues, and make it easier to evaluate how well treatments like chemotherapy, radiation, or immunotherapy are working.

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